New PDF release: C-H Bond Activation in Organic Synthesis

By Jie Jack Li

ISBN-10: 148223310X

ISBN-13: 9781482233100

C–H activation comprises any of quite a lot of concepts, frequently utilizing catalysts within which a carbon to hydrogen covalent bond of an natural compound is cleaved to switch the hydrogen with a useful workforce. C–H Activation for functionalization is the state-of-the-art in natural chemistry. It allows chemists to hold out reactions within the so much environmentally pleasant model with the least infection of by-products. Written via an writer skilled during this swiftly constructing the sphere, this booklet covers C–H activation via quite a few catalysts.

Show description

Read or Download C-H Bond Activation in Organic Synthesis PDF

Best organic books

Download PDF by John Meurig Thomas, W. John Thomas: Principles and Practice of Heterogeneous Catalysis

Catalysis occupies a pivotal place within the actual and organic sciences. in addition to being the mainstay of the chemical undefined, it's the technique of effecting many laboratory syntheses and the basis reason for all enzymatic techniques. This ebook is an eminently readable advent to the elemental rules of heterogeneous catalysis.

Download PDF by B. M. Trost, I. Fleming: Comprehensive Organic Synthesis - Selectivity, Strategy and

The advance of greater routes to recognized fabrics and the construction of latest fabrics are very important targets in lots of components, together with electronics, agriculture, drugs and textiles. natural synthesis is important to attaining those targets. accomplished natural Synthesisdraws jointly the typical topics that underlie the various it appears disparate components of natural chemistry which underpin artificial suggestions, therefore delivering a accomplished assessment of this significant self-discipline.

Additional resources for C-H Bond Activation in Organic Synthesis

Sample text

Along with the diminished regioselectivity, polychlorination is common. 13 Br Br H Br Br H Br Br Br Non-functionalized alkanes are preferentially brominated at tertiary carbon atoms in preference to primary or secondary positions, with selectivity decreasing with increasing temperature. 15 Hydrogen-atom abstraction occurs readily at carbon atoms α to an ether. 2 Radical Allylic and Benzylic Halogenation (Wohl–Ziegler Bromination) As mentioned above, attempts to affect radical halogenation using elemental halogen is complicated when the substrate contains an alkene, as electrophilic addition of X2 across the alkene predominates.

Res. 2011, 45, 864–873. 115. Arockiam, P. ; Dixneuf, P. H. Chem. Rev. 2012, 112, 5879–5918. 116. ; Chatani, N. Nature 1993, 366, 529–531. 117. ; Clot, E. Chem. Eur. J. 2012, 18, 11449–11458. 118. ; Muzart, J. Chem. Rev. 2011, 111, 1170–1214. 119. ; Murai, S. Chem. Lett. 1998, 27, 1053–1054. 20 C―H Bond Activation in Organic Synthesis 120. ; Vicente, R. Ruthenium-Catalyzed Direct Arylations Through C―H Bond Cleavages. , Eds. Springer: Berlin, Heidelberg: 2010; Vol. 292, pp 211–229. ; Inoue, Y. Ortho-selective allylation of 2-pyridylarenes with allyl ­acetates catalyzed by ruthenium complexes.

20 C―H Bond Activation in Organic Synthesis 120. ; Vicente, R. Ruthenium-Catalyzed Direct Arylations Through C―H Bond Cleavages. , Eds. Springer: Berlin, Heidelberg: 2010; Vol. 292, pp 211–229. ; Inoue, Y. Ortho-selective allylation of 2-pyridylarenes with allyl ­acetates catalyzed by ruthenium complexes. Organometallics 2006, 25, 4773–4778. ; Uemura, S. Organometallics 2004, 23, 5841–5848. 123. Foley, N. ; Lee, J. ; Gunnoe, T. ; Cundari, T. ; Petersen, J. L. J. Am. Chem. Soc. 2007, 129, 6765–6781.

Download PDF sample

C-H Bond Activation in Organic Synthesis by Jie Jack Li


by David
4.1

Rated 4.56 of 5 – based on 38 votes