Read e-book online Biological Rhythms PDF

By Jürgen Aschoff (auth.), Jürgen Aschoff (eds.)

ISBN-10: 1461565529

ISBN-13: 9781461565529

ISBN-10: 1461565545

ISBN-13: 9781461565543

Interest in organic rhythms has been traced again greater than 2,500]ears to Archilochus, the Greek poet, who in a single of his fragments indicates ",,(i,,(VWO'KE o'olos pv{}J.tos txv{}pW7rOVS ~XH" (recognize what rhythm governs guy) (Aschoff, 1974). Reference can be made to the French pupil of drugs J. J. Virey who, in his thesis of 1814, used for the 1st time the expression "horloge vivante" (living clock) to explain day-by-day rhythms and to D. C. W. Hufeland (1779) who referred to as the 24-hour interval the unit of our traditional chronology. even if, it used to be now not till the Thirties that actual growth used to be made within the research of organic rhythms; and Erwin Bunning was once inspired to put up the 1st, and nonetheless now not superseded, monograph within the box in 1958. years later, in the course of fascinating discoveries, we took a breather on the chilly Spring Harbor Symposium on organic Clocks. Its survey on ideas thought of legitimate at the moment, and Pittendrigh's expecting view at the temporal association of residing structures, made it a milestone on our means from a extra formalistic description of organic rhythms to the knowledge in their structural and physiological basis.

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Numerical signal averaging, on the other hand, is closely related to periodogram analysis. A comparative evaluation of progressive Fourier analysis and numerical signal averaging has been undertaken by Martin and Brinkmann (1977). Their conclusions bear out the preceding comments on the relative merits of Fourier analysis and periodogram procedures: periodogram-related methods are more economical of computer time, often by orders of magnitude, with no loss in reliability or reproducibility of the estimated values of period.

71). MEASUREMENT OF PHASE SHIFT The response to a single-pulse stimulus, illustrated in the final portion of Figure 1, is an idealized and very clear result, but the interpretation and proper quantification of such experiments deserve further consideration. Problems arise because the issue of fundamental interest in circadian-rhythm studies is usually the effect of the stimulus on the pacemaker that underlies the observed rhythm and not simply the effect on the rhythm itself. As a first precaution, it is therefore necessary to observe the rhythm for several cycles following the stimulus.

One of the most important of the environmental variables to be chosen is the intensity of constant light (or darkness) provided. Constant bright light frequently inhibits the expression of circadian rhythmicity in organisms at all phyletic levels, and the intensity of light that suppresses rhythmicity is often surprisingly low. 5 lux (Miselis and Walcott, 1970). For poikilotherms, the constant temperature provided must also be appropriate, with a loss of rhythmicity often reported at temperatures under 1Q°C.

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Biological Rhythms by Jürgen Aschoff (auth.), Jürgen Aschoff (eds.)


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